• Clinical imaging · Mar 2016

    Review

    The evidence for low-dose CT screening of lung cancer.

    • Kathleen Ruchalski, Antonio Gutierrez, Scott Genshaft, Fereidoun Abtin, and Robert Suh.
    • David Geffen School of Medicine at UCLA, Department of Radiology, 757 Westwood Plaza, Ste 1621, Los Angeles, CA, 90095-1721. Electronic address: kruchalski@mednet.ucla.edu.
    • Clin Imaging. 2016 Mar 1; 40 (2): 288-95.

    AbstractLung cancer remains the leading cause of cancer-related death in the United States. An effective screening tool for early lung cancer detection has long been sought. Early chest radiograph and low-dose computed tomography (LDCT) screening trials were promising and demonstrated increased cancer detection. However, these studies were not able to improve lung cancer mortality. The National Lung Screening Trial resulted in decreased lung cancer mortality with LDCT screening in a high-risk population. Similar trials are currently underway in Europe. With LDCT now being widely implemented, it is paramount for radiologists to understand the evidence for lung cancer screening. Copyright © 2015 Elsevier Inc. All rights reserved.

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