• World Neurosurg · Dec 2019

    Preservation of olfactory function following endoscopic single nostril transseptal transsphenoidal surgery Running head: Preservation of olfactory function following TSS.

    • Teppei Kawabata, Kazuhito Takeuchi, Yuichi Nagata, Takayuki Ishikawa, Jungsu Choo, Yusuke Sato, Masao Tambara, Masaaki Teranishi, and Toshihiko Wakabayashi.
    • Department of Neurosurgery, Graduate School of Medicine, Nagoya University, Nagoya, Japan. Electronic address: kawabata.teppei@b.mbox.nagoya-u.ac.jp.
    • World Neurosurg. 2019 Dec 1; 132: e665-e669.

    ObjectiveOlfactory dysfunction is a significant postoperative complication related to endoscopic transsphenoidal surgery (TSS). This study aimed to determine the impact of endoscopic TSS on olfactory function.MethodsWe conducted a prospective study of 32 patients with sellar or parasellar tumors who were treated with endoscopic TSS between December 2013 and October 2016. TSS was performed via a right transseptal approach. We performed the Toyota and Takagi olfactometer test and the venous olfaction test for the evaluation of olfactory function preoperatively and at 1 and 3 months postoperatively.ResultsThe results of the Toyota and Takagi test showed that olfactory function deteriorated in 4 of 32 (12.5%) patients 1 month postoperatively and improved to preoperative baseline levels in all patients 3 months after the procedure. Olfactory function deteriorated in 1 of 31 (3.2%) patients 3 months after the procedure. The venous olfaction test revealed no response in 1 of 31 (3.2%) patients 1 month postoperatively, with no improvement 3 months after the procedure.ConclusionsEndoscopic single-nostril transseptal TSS for sellar or parasellar tumor resection has minimal impact on olfactory function.Copyright © 2019 Elsevier Inc. All rights reserved.

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