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Ann Fr Anesth Reanim · Apr 2002
Case Reports[Severe pneumococcal meningitis and ceftriaxone allergy].
- S Mérat, J M Rousseau, M Lerecouvreux, I Vincenti-Rouquette, and L Brinquin.
- Département d'anesthésie-réanimation, hôpital d'instruction des armées du Val de Grâce, 74, boulevard de Port Royal, 75005, Paris, France. schmart@free.fr
- Ann Fr Anesth Reanim. 2002 Apr 1; 21 (4): 295-8.
AbstractWe report the case of a 51-year-old man with an allergy to amoxicillin/acid clavulanique who presented with Streptococcus pneumoniae meningitis. Initial treatment consisted of an association of antibiotics including ceftriaxone. Six days after treatment was initiated the patient developed skin reaction and the diagnosis of allergy to ceftriaxone was established by the dosage of specific IgE. Typically Streptococcus pneumoniae meningitis is treated with vancomycin and a third-generation cephalosporin. This association had to be modified because cross allergy to cephalosporins could have developed in this patient who had previously reacted to penicillins.
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