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- L Dumont, C Lysakowski, and B Kayser.
- Division d'anesthésiologie, hôpitaux universitaires de Genève, rue Micheli-du-Crest, 24 CH-1211 14, Genève, Suisse. alpamayo98@yahoo.com <alpamayo98@yahoo.com>
- Ann Fr Anesth Reanim. 2003 Apr 1; 22 (4): 320-4.
AbstractAcute mountain sickness and high altitude cerebral edema are specific pathologies of high altitude exposure. The usual symptoms of acute mountain sickness are headache, nausea, vomiting, insomnia, lassitude, dizziness and ataxia. High altitude cerebral oedema is a severe state of acute mountain sickness with, in addition, alteration of mental status and consciousness. The pathophysiology of these 2 diseases are essentially due to an increase of intracranial pressure directly dependent of an increase of cerebral volume. Molecular and cellular mechanisms underlying acute mountain sickness and high altitude cerebral oedema are still poorly understood. The regulation of cerebral blood flow by nitric oxide seems to play a major role.
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