• World Neurosurg · Dec 2019

    Review Case Reports

    Adult-onset mixed germ cell tumor composed mainly of yolk sac tumor around the pineal gland: a case report and review of the literature.

    • Hiroshi Uda, Takehiro Uda, Kosuke Nakajo, Yuta Tanoue, Takahiro Okuno, Saya Koh, Yohei Onishi, Hiroki Ohata, Yusuke Watanabe, Ryoko Umaba, Toshiyuki Kawashima, and Kenji Ohata.
    • Department of Neurosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
    • World Neurosurg. 2019 Dec 1; 132: 87-92.

    BackgroundMixed germ cell tumors (MGCTs) usually occur in children. In the present report, we discuss an extremely rare case of adult-onset MGCT composed mainly of yolk sac tumor (YST) around the pineal gland.Case DescriptionA 54-year-old Japanese man presented with disturbance of consciousness, Parinaud's syndrome, and gait disturbance. Magnetic resonance imaging revealed a pineal mass lesion, and subtotal resection of the tumor was achieved. The histologic diagnosis was MGCT, consisting mainly of YST. Although he underwent 5 courses of chemotherapy and craniospinal irradiation after surgery, tumor dissemination could not be controlled, and he died 10 months postoperatively.ConclusionThe present case highlights the need for clinicians to include YST in the differential diagnosis of acute progressive lesions around the pineal region, even in adult patients.Copyright © 2019 Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…