• Neuroscience · Nov 2019

    In Vitro Optogenetic Characterization of Neuropeptide Release from Prefrontal Cortical Somatostatin Neurons.

    • Nigel C Dao, Dakota F Brockway, and Nicole A Crowley.
    • Department of Biobehavioral Health, Pennsylvania State University, University Park, PA 16802.
    • Neuroscience. 2019 Nov 1; 419: 1-4.

    AbstractSomatostatin is a neuropeptide thought to play a role in a variety of neuropsychiatric disorders, and is important for healthy aging and behavioral resiliency. Physiological conditions underlying somatostatin peptidergic release are not well-defined. Using a combination of optogenetic and biochemical approaches in transgenic mice, we demonstrate an assay for the induction and inhibition of somatostatin release in mouse acute brain slices.Copyright © 2019 IBRO. Published by Elsevier Ltd. All rights reserved.

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