• B K Mokriski and A M Malinow.
• Department of Anesthesiology, University of Maryland School of Medicine, Baltimore 21201.
• J Clin Anesth. 1992 Mar 1; 4 (2): 97-100.

Study ObjectiveTo determine whether halothane or isoflurane as anesthesia for emergency abdominal delivery is associated with better fetal acid-base parameters.DesignRandomized study.SettingInpatient Level III perinatal referral center in a university hospital.PatientsSixty-six gravidas undergoing emergency abdominal delivery under general anesthesia for fetal distress.InterventionsRandomization to receive halothane or isoflurane at 0.7 minimum alveolar concentration as part of a standard anesthetic technique.Measurements And Main ResultsUmbilical artery and vein blood gases were obtained and compared for hydrogen ion concentration, partial pressure of carbon dioxide, partial pressure of oxygen, and base deficit. There were no significant differences between the isoflurane and halothane groups.ConclusionsThere is no difference in the frequency or severity of acidosis associated with isoflurane or halothane when used for general anesthesia for emergency abdominal delivery of a distressed fetus.

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