• J Clin Anesth · Sep 1992

    Comparative Study

    Comparison of pregnancy rates following gamete intrafallopian transfer (GIFT) under general anesthesia with thiopental sodium or propofol.

    • E T Pierce, M Smalky, M M Alper, J A Hunter, R L Amrhein, and E C Pierce.
    • Department of Anaesthesia, Harvard Medical School, Boston, MA.
    • J Clin Anesth. 1992 Sep 1; 4 (5): 394-8.

    Study ObjectiveTo determine whether the pregnancy rate for gamete intrafallopian transfer (GIFT) patients who received thiopental sodium was different from the pregnancy rate for patients who received propofol for the induction of general anesthesia.DesignRetrospective review of clinical records.SettingPrivate outpatient infertility clinic.PatientsTwo hundred eighty-two consecutive GIFT procedures performed on 230 patients with infertility.InterventionPatients undergoing GIFT were divided into two groups on the basis of whether they received thiopental or propofol for induction of anesthesia.Measurements And Main ResultsClinical pregnancy following each GIFT procedure was assessed by multiple-serum beta human chorionic gonadotropin and ultrasound determinations. The pregnancy rates of 24.6% and 25.8% for the thiopental and propofol groups, respectively, were not significantly different.ConclusionsThe pregnancy rate following GIFT for patients given propofol for induction of general anesthesia did not differ from that for patients given thiopental.

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