• J Neuroimaging · Jan 2013

    Clinical Trial

    Trevo System: single-center experience with a novel mechanical thrombectomy device.

    • Nuno Mendonça, Alan Flores, Jorge Pagola, Marta Rubiera, David Rodríguez-Luna, M Angels De Miquel, Pere Cardona, Helena Quesada, Paloma Mora, José Alvarez-Sabín, Carlos Molina, and Marc Ribó.
    • Department of Neurology, University Hospital of Coimbra, Coimbra, Portugal.
    • J Neuroimaging. 2013 Jan 1;23(1):7-11.

    Background And PurposeRecent reports have indicated that mechanical thrombectomy may have the potential to treat acute ischemic stroke. This study aims to describe the safety and effectiveness of Trevo Retriever, using Stentriever technology, in revascularization of patients with acute ischemic stroke.MethodsProspective study evaluating the clinical, radiological, and functional outcome of 13 patients with an angiographically verified occlusion of the anterior cerebral circulation. All patients underwent thrombectomy with TR as monotherapy or in combination with intra-arterial thrombolysis, within the first 8 hours from the onset of symptoms. Successful revascularization was defined as thrombolysis in cerebral ischemia grade 2a to 3. Good outcome was defined as modified Rankin Scale score ≤ 2.ResultsMedian baseline National Institutes of Health Stroke Scale score was 19(16-22). The occlusion site was middle cerebral artery in 8 patients and internal carotid artery in 5 patients. Revascularization was achieved in 10 of 13 patients (77%). The mean time from groin puncture to recanalization was 95 ± 31 minutes. No significant intra-procedural complications occurred. Four patients (30%) died during the 90-day follow-up period and 4 patients (30%) achieved functional independence.ConclusionEarly clinical experience suggests that the TR can allow safe and effective revascularization in certain subjects with acute ischemic stroke.Copyright © 2011 by the American Society of Neuroimaging.

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