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- Sven O'hEireamhoin, John F Quinlan, and Kieran O Rourke.
- Department of Trauma and Orthopaedics, St. Vincent's University Hospital, Elm Park, Dublin, Ireland. svenerwin@hotmail.com
- Orthop Surg. 2011 Feb 1; 3 (1): 40-4.
ObjectiveTo assess the rate of clinical and radiological union with the use of bone morphogenetic protein 7 (BMP-7) in a range of fractures.MethodsThis case series retrospectively reviews a series of 16 fracture non-unions in 13 patients. These patients were treated with the commercially available BMP-7. Time to radiological and clinical union was assessed by serial out-patient follow-up.ResultsAt nine months post-surgery in which BMP-7 was added, 12 of 16 non-unions had achieved clinical and radiographic union. Three patients required repeat grafting. The mean time to union was 5.1 ± 1.6 months after the application of BMP-7.ConclusionThe use of the osteo-inductive agent, BMP-7 results in good clinical and radiological outcomes which are not restricted to tibial non-unions.© 2011 Tianjin Hospital and Blackwell Publishing Asia Pty Ltd.
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