• Neuroimaging Clin. N. Am. · May 2013

    Review

    Pediatric multiple sclerosis: pathobiological, clinical, and magnetic resonance imaging features.

    • Leonard H Verhey, Manohar Shroff, and Brenda Banwell.
    • Pediatric Demyelinating Disease Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
    • Neuroimaging Clin. N. Am.. 2013 May 1;23(2):227-43.

    AbstractIn this article, the pathobiological, clinical, and treatment aspects of pediatric-onset multiple sclerosis (MS) are summarized, and the conventional magnetic resonance (MR) imaging (ie, T1-weighted, proton-density, and T2-weighted imaging) features of MS in children are discussed, as well as the application of MR imaging in the diagnosis of pediatric-onset MS and in prediction of MS in children with an incident central nervous system demyelination. Insights gained from studies comparing MR imaging features of pediatric-onset and adult-onset MS are presented.Copyright © 2013 Elsevier Inc. All rights reserved.

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