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- Marc O Maybauer and Dirk M Maybauer.
- a a Critical Care Research Group, The University of Queensland and the Prince Charles Hospital , Brisbane , Queensland , Australia.
- Curr Med Res Opin. 2015 Jan 1; 31 (10): 1829-30.
AbstractRecent promising findings indicate a possible benefit of β-blockade in septic patients. Ongoing trials on esmolol in septic shock are investigating its hemodynamic effects, focusing on heart rate control and echocardiographic changes, as well as potential anti-inflammatory effects. However, given the complex physiology of sepsis and pharmacological effects on β-blockade, large multi-center trials are essential before such a therapy may be applied safely.
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