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Randomized Controlled Trial
Superior hypogastric plexus block as a new method of pain relief after abdominal hysterectomy: double-blind, randomised clinical trial of efficacy.
- H Rapp, S Ledin Eriksson, and P Smith.
- Department of Gynaecology and Obstetrics, Gävle Hospital, Gävle, Sweden.
- BJOG. 2017 Jan 1; 124 (2): 270-276.
ObjectiveTo determine whether superior hypogastric plexus block performed during abdominal hysterectomy decreases postoperative opioid consumption and pain.DesignA randomised, double-blind, placebo-controlled, clinical trial.SettingA county hospital in Sweden.PopulationSixty-eight women scheduled for total abdominal hysterectomy for a benign indication.MethodsTwenty ml of ropivacaine 7.5 mg/ml or saline was injected retroperitoneally in the area of the superior hypogastric plexus during the hysterectomy. The participants were individually randomised to either intervention. The participants, caregivers, and those assessing the outcomes were blinded to group assignment.Main Outcome MeasuresThe primary outcomes were postoperative opiate consumption and patients' self-assessment of pain (VAS scores). Secondary outcomes were mobilisation and side effects related to opiate consumption.ResultsThe trial was completed with 38 women randomised to ropivacaine and 37 women randomised to saline. Analysis was performed on 35 women in the ropivaciane group and 33 women in the saline group. The postoperative opioid consumption was significantly lower in the ropivacaine group than in the placebo group (median 55.8 and 72.4 mg, respectively, P = 0.032). The proportion of women scoring VAS <4 at 2 hours after block was significantly higher in the ropivacaine group (63%) than in the placebo group (25%) (P = 0.015). No side effects or important adverse events occurred during the trial.ConclusionsThe superior hypogastric plexus block is a new method in this context and a promising contribution to postoperative pain treatment after abdominal hysterectomy.Tweetable AbstractSuperior hypogastric plexus block during abdominal hysterectomy lowers opioid consumption.© 2016 Royal College of Obstetricians and Gynaecologists.
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