BJOG : an international journal of obstetrics and gynaecology
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Randomized Controlled Trial Multicenter Study
Diagnostic workup for postmenopausal bleeding: a randomised controlled trial.
To evaluate the effectiveness of hysteroscopy for the detection and treatment of endometrial polyps versus expectant management in women with postmenopausal bleeding (PMB), a thickened endometrium and benign endometrial sampling. ⋯ In women with PMB, hysteroscopy does not reduce recurrent bleeding but is warranted to detect focal malignancy.
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The contraceptive injectable is a safe and effective method that is used worldwide. With the variety of injectable delivery systems, there is potential for administration by the woman herself. Self-administration of the contraceptive injectable is the subject of this systematic review. ⋯ This review assessed the continuation rates and safety of self-administration of the contraceptive injection.
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Randomized Controlled Trial
Superior hypogastric plexus block as a new method of pain relief after abdominal hysterectomy: double-blind, randomised clinical trial of efficacy.
To determine whether superior hypogastric plexus block performed during abdominal hysterectomy decreases postoperative opioid consumption and pain. ⋯ Superior hypogastric plexus block during abdominal hysterectomy lowers opioid consumption.
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Localised provoked vulvodynia (LPV) is a common, chronic, and disabling condition: patients experience profound pain and a diminished quality of life. The aetiologic origins of vulvodynia are poorly understood, yet recent evidence suggests a link to site-specific inflammatory responses. ⋯ Although LPV is a multifactorial disorder, understanding vulvar inflammation and targeting the inflammatory response should lead to treatment advances, especially for patients exhibiting signs of inflammation. NFκB (already targeted clinically) or other inflammatory components may be suitable therapeutic targets.