• Eur J Emerg Med · Jun 1999

    Case Reports

    Concurrent administration of amrinone with nitric oxide most improves PaO2/FiO2 in acute respiratory and cardiac failure.

    • H Yukioka, M Hayashi, T Yamada, and M Fujimori.
    • Division of Critical Care Medicine, Osaka City University Medical School, Japan.
    • Eur J Emerg Med. 1999 Jun 1; 6 (2): 161-4.

    AbstractA 55-year-old man developed acute respiratory failure, pulmonary hypertension and left heart failure due to acute myocardial infarction. Nitric oxide (NO) inhalation improved arterial oxygenation, decreased pulmonary arterial pressure and increased cardiac output (CO), but combined use of dobutamine with NO produced increases in pulmonary arterial pressure and pulmonary capillary wedge pressure (PCWP). In this patient, amrinone decreased pulmonary arterial pressure and PCWP, and increased PaO2/FiO2 effectively while increasing CO. Combined use of inhaled NO and intravenous amrinone may have beneficial effects for a patient with acute respiratory and cardiac failure.

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