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Critical care clinics · Jan 2020
ReviewSoluble Triggering Receptor Expressed on Myeloid Cells-1: Diagnosis or Prognosis?
- Jérémie Lemarié and Sébastien Gibot.
- CHRU Nancy, Hôpital Central, Service de Réanimation Médicale, 29 avenue de LAttre de Tassigny, 54000 Nancy, France; INSERM UMRS-1116, Faculté de Médecine Nancy, Université de Lorraine, 9 avenue de la forêt de Haye, 54500 Vandoeuvre-les-Nancy, France.
- Crit Care Clin. 2020 Jan 1; 36 (1): 41-54.
AbstractThe diagnosis of sepsis, and especially its differentiation from sterile inflammation, may be challenging. The triggering receptor expressed on myeloid cells-1 is an amplifier of the innate immune response. Its soluble form is detectable in various biological fluids and can be used as a surrogate marker of triggering receptor expressed on myeloid cells-1 activation. In this article, we review the abundant literature evaluating the usefulness of soluble triggering receptor expressed on myeloid cells-1 for the diagnosis and the prognosis evaluation of sepsis or localized infections.Copyright © 2019 Elsevier Inc. All rights reserved.
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