• Minerva anestesiologica · Oct 2011

    WITHDRAWN Coronary artery spasm associated with blood brain barrier disruption induced by carotid sinus stimulation.

    • S S Zaky, G H Barnett, A A Abd-Elsayed, and E Farag.
    • Anesthesia Institute, Cleveland Clinic, Cleveland, Ohio, USA alaaawny@hotmail.com.
    • Minerva Anestesiol. 2011 Oct 21.

    AbstractAhead of Print article withdrawn by publisher Blood brain barrier disruption (BBBD) is a novel technique for treating central nervous system lymphoma. This technique depends on the disruption of the tight junctions between endothelial cells (which represent the blood brain barrier) by intra-arterial injection of mannitol. The most common complications of blood brain barrier disruption are seizures and brain edema. Here, the authors present a rare complication of coronary artery spasm manifested by elevation of the ST segment and bradycardia due to carotid sinus stimulation in a 33 year-old-male during blood brain barrier disruption. To the authors' knowledge, this is the first report of a coronary artery spasm complicating blood brain barrier disruption.

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