• Neuroimaging Clin. N. Am. · Feb 2020

    Review

    The Neurodevelopment of Autism from Infancy Through Toddlerhood.

    • Jessica B Girault and Joseph Piven.
    • Carolina Institute for Developmental Disabilities, The University of North Carolina at Chapel Hill School of Medicine, 101 Renee Lynne Court, Chapel Hill, NC 27599, USA. Electronic address: jbgirault@unc.edu.
    • Neuroimaging Clin. N. Am. 2020 Feb 1; 30 (1): 97-114.

    AbstractAutism spectrum disorder (ASD) emerges during early childhood and is marked by a relatively narrow window in which infants transition from exhibiting normative behavioral profiles to displaying the defining features of the ASD phenotype in toddlerhood. Prospective brain imaging studies in infants at high familial risk for autism have revealed important insights into the neurobiology and developmental unfolding of ASD. In this article, we review neuroimaging studies of brain development in ASD from birth through toddlerhood, relate these findings to candidate neurobiological mechanisms, and discuss implications for future research and translation to clinical practice.Copyright © 2019 Elsevier Inc. All rights reserved.

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