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J. Toxicol. Clin. Toxicol. · Jan 1995
Case ReportsColchicine toxicity--clinical features and treatment. Massive overdose case report.
- A Folpini and P Furfori.
- Department of Anaesthesia, Intensive Care and Pain Therapy, Ospedale Regionale, Massa, Italy.
- J. Toxicol. Clin. Toxicol. 1995 Jan 1; 33 (1): 71-7.
AbstractThis is a report of colchicine poisoning in a 24-year-old woman. She developed multiple organ failure and bone marrow suppression after the suicidal ingestion of 50 (1 mg) colchicine tablets. The pancytopenia responded to granulocyte colony-stimulating factor 300 micrograms on days 4, 5, 6, and 8. Although anticolchicine monoclonal antibody administration is the only specific therapy described, intensive supportive care including granulocyte colony-stimulating factor administration can facilitate recovery from severe colchicine intoxication.
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