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Comparative Study
Comparison of the seroprevalence of human metapneumovirus and human respiratory syncytial virus.
- Takashi Ebihara, Rika Endo, Hideaki Kikuta, Nobuhisa Ishiguro, Hiroaki Ishiko, and Kunihiko Kobayashi.
- Department of Pediatrics, Hokkaido University School of Medicine, Sapporo, Japan.
- J. Med. Virol. 2004 Feb 1; 72 (2): 304-6.
AbstractHuman metapneumovirus (hMPV) is a virus that induces human respiratory syncytial virus (hRSV)-like illnesses, ranging from upper respiratory tract infection to severe bronchiolitis and pneumonia. The 100 serum samples from children aged 1 month to 5 years were tested for the presence of hMPV and hRSV antibodies using an indirect immunofluorescence assay and a neutralizing-antibody assay, respectively. The seroprevalence of hMPV was significantly lower than that of hRSV in children over 4-months-old (43% vs. 60%, P < 0.025), and the difference was particularly notable between the ages of 4 months and 1 year (11% vs. 48%, P = 0.006). The results suggest that primary infection with hMPV occurs somewhat later than that with hRSV.Copyright 2004 Wiley-Liss, Inc.
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