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- Robert R Rozeske, Benjamin N Greenwood, Monika Fleshner, Linda R Watkins, and Steven F Maier.
- University of Colorado-Boulder, Department of Psychology and Neuroscience, Muenzinger Building, UCB 345, Boulder, CO 80309, USA. rozeske@colorado.edu
- Behav. Brain Res. 2011 Jun 1; 219 (2): 378-81.
AbstractIn rodents, exposure to acute inescapable, but not escapable, stress potentiates morphine conditioned place preference (CPP), an effect that is dependent upon hyperactivation of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN). Six weeks of voluntary wheel running constrains activation of DRN 5-HT neurons during exposure to inescapable stress. Six weeks of voluntary wheel running before inescapable stress blocked stress-induced potentiation of morphine CPP.Published by Elsevier B.V.
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