• Lung Cancer · May 2008

    Case Reports

    Stepwise progression from ground-glass opacity towards invasive adenocarcinoma: long-term follow-up of radiological findings.

    • Hiroshi Soda, Yoichi Nakamura, Katsumi Nakatomi, Nanae Tomonaga, Hiroyuki Yamaguchi, Hirofumi Nakano, Seiji Nagashima, Masanobu Anami, Tomayoshi Hayashi, Kazuhiro Tsukamoto, and Sigeru Kohno.
    • Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki 852-8501, Japan. h-souda@hospital.sasebo.nagasaki.jp
    • Lung Cancer. 2008 May 1; 60 (2): 298-301.

    AbstractThe natural history of lung adenocarcinoma with ground-glass opacity (GGO) remains undetermined. We describe a lung adenocarcinoma in which GGO transformed through a scar-like lesion over the long term into a solid nodule of poorly differentiated adenocarcinoma. Whether poorly differentiated lung adenocarcinoma can evolve from GGO-type adenocarcinoma is an important issue that requires clarification.

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