• Fernanda de Carvalho Pazzini Maia, Thales Antônio Silva, Generoso Simone de Vasconcelos SV Department of Nutrition, Nursing School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., and Correia Maria Isabel Toulson Davisson MITD Department of Surgery, Medical School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic a.
• Food Sciences Post Graduation Program, Pharmacy School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
• Nutrition. 2020 Jul 1; 75-76: 110769.

ObjectiveThe aim of this study was to evaluate the association between preoperative nutritional status and health-related quality of life (HRQoL) in patients with gastrointestinal cancer who were admitted for elective surgical treatment.MethodsThis was a cross-sectional study in which patients with a diagnosis of gastrointestinal cancer were evaluated before a surgical procedure. The nutritional assessment included subjective global assessment (SGA) and measurements of weight loss percentage, bioelectrical impedance, and functional capacity. HRQoL was evaluated by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). Statistical analyses were performed with a significance level of 5%. The sample size was calculated based on a pilot study.ResultsWe evaluated 132 patients, the majority of whom were men. The median age of the patients was 62 y, and the most prevalent tumors were in the colon, rectum, and anus (52.3%). The SGA highlighted the high prevalence of malnutrition (69.9%), which was confirmed by the rates of weight loss (73.8%) and the low fat-free mass index (56.8%). Malnourished patients and patients with severe weight loss had worse functional, symptom, global health and quality of life scores (P < 0.05). Malnutrition, according to the SGA, decreased physical function and role performance scores by 9 and 20 points, respectively (P < 0.05).ConclusionMalnutrition, assessed by various tools, was associated with poor HRQoL of surgical patients with gastrointestinal cancer.Copyright © 2020 Elsevier Inc. All rights reserved.

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