• World Neurosurg · Aug 2020

    Case Reports

    Granular Cell Tumour of the Pituitary presenting with major intraventricular haemorrhage.

    • Wim Maenhoudt, Jo Van Dorpe, and Dimitri Vanhauwaert.
    • Department of Neurosurgery, AZ Delta, Roeselare, Belgium. Electronic address: wim.maenhoudt@gmail.com.
    • World Neurosurg. 2020 Aug 1; 140: 60-62.

    AbstractGranular cell tumors of the pituitary gland are rare, slow-growing lesions arising from the neurohypophysis or pituitary stalk. We describe an extremely rare presentation of a pituitary granular cell tumor mimicking an anterior communicating artery aneurysmal rupture with ventricular hemorrhage. The patient was admitted in a comatose state and underwent urgent bilateral external ventricular drainage. Further diagnostic investigation revealed a sellar tumoral mass with suprasellar extension. No vascular anomalies, hormonal abnormalities, or visual disturbances were observed. Macroscopic complete resection without neurologic impairment was obtained via a right pterional approach. Posthemorrhagic hydrocephalus necessitated ventriculoperitoneal shunt placement, and hormonal substitution for panhypopituitarism was provided. The 5-year follow-up examination showed no tumor recurrence. The clinical course of these benign World Health Organization grade I lesions will normally correspond to nonsecreting pituitary adenomas with an insidious development of visual disturbances, hypopituitarism, or hydrocephalus. Sudden onset with potential catastrophic intratumoral and intraventricular hemorrhage is very uncommon.Copyright © 2020 Elsevier Inc. All rights reserved.

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