• Dong Young Cho, Jai Ho Choi, Hyun Seok Choi, Bum-Soo Kim, and Yong Sam Shin.
• Department of Neurosurgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea; Department of Neurosurgery, Ewha Woman's University Seoul Hospital, Ewha Woman's University College of Medicine, Seoul, Republic of Korea.
• World Neurosurg. 2020 Sep 1; 141: e151-e159.

BackgroundWe hypothesized that the immediate postoperative imaging features would be associated with early regression of flow-diverted aneurysms. We compared the imaging features from digital subtraction angiography and spin echo T2-weighted magnetic resonance imaging between those with early total regression and partial regression.MethodsA total of 30 consecutive patients with large and giant aneurysms were treated with pipeline embolization devices and divided into 2 groups according to the follow-up angiographic findings at 3-6 months. Of the 30 patients, 20 had had total or near total regression and 10 had had partial regression of the aneurysmal sac. The baseline characteristics, percent area of stagnated iodine contrast agent on anteroposterior and lateral angiographic views just after installation of the pipeline device, and median, minimal, and 10-percentile signal intensity of the aneurysmal sac on T2-weighted spin echo images 1 day after the procedure were compared between the 2 groups.ResultsA comparison of the demographic data between the 2 groups showed no significant differences. The volume of the treated aneurysmal sac also did not differ significantly (2559.28 ± 3021.45 mm3 vs. 2551.76 ± 6550.58 mm3; P = 0.455). The total or near total regression group had a larger percent area of iodine stagnation on the lateral angiographic view compared with the partial regression group (52.26% vs. 23.35%; P = 0.002). The median, minimal, and 10-percentile signal intensity of the volume of interest were higher in the total or near total regression group than in the partial regression group (1.29 vs. 0.93 [P = 0.025]; 0.07 vs. 0.00 [P = 0.042]; 0.57 vs. 0.24 [P = 0.005]).ConclusionsThe percent area of contrast media stagnation on lateral angiograms and the median, minimal, and 10th-percentile signal intensity of the volume of interest of treated aneurysmal sacs on T2-weighted images can be used to predict early regression of aneurysmal sacs.Copyright © 2020 Elsevier Inc. All rights reserved.

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