• Dana Ganor-Stern, Yarden Gliksman, Sharon Naparstek, Gal Ifergane, and Avishai Henik.
• Department of Psychology, Achva Academic College, MP. Shikmim 79800, Israel. Electronic address: dana_g@achva.ac.il.
• Neuroscience. 2020 Jul 1; 438: 137-144.

AbstractPast research investigating the role of the intraparietal sulcus (IPS) in numerical processes focused mainly on quantity and numerical comparisons as well on single digit arithmetic. The present study investigates the involvement of the IPS in estimating the results of multi-digit multiplication problems. For this purpose, the performance a 24-year-old female (JD) with brain damage in the left IPS was compared to an age-matched control group in the computation estimation task. When required to estimate whether the results of multi-digit multiplication problems are smaller or larger than given reference numbers, JD, in contrast to controls, did not show the common patterns of distance and size effects. Her strategy use was also atypical. Most control participants used both the approximated calculation strategy that involves rounding and calculation procedures and the sense of magnitude strategy that relies on an intuitive approximated magnitude representation of the results. In contrast, JD used only the former but not the latter strategy. Together, these findings suggest that the damage to the IPS impaired JD's representations of magnitude that play an important role in this computation estimation task.Copyright © 2020 IBRO. Published by Elsevier Ltd. All rights reserved.

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