• A Auvinen, M Hakama, H Arvela, T Hakulinen, T Rahola, M Suomela, B Söderman, and T Rytömaa.
• Finnish Centre for Radiation and Nuclear Safety, Helsinki.
• BMJ. 1994 Jul 16; 309 (6948): 151-4.

ObjectiveTo assess effects of fallout from Chernobyl on incidence of childhood leukaemia in Finland.DesignNationwide cohort study. External exposure measured for 455 Finnish municipalities with instruments driven 19,000 km throughout the country. Values specific to municipalities corrected for shielding due to houses and fallout from A bomb testing. Internal exposure estimated from whole body measurements on a random sample of 81 children. Mean effective dose for two years after incident calculated from these measurements. Data on childhood leukaemia obtained from Finnish cancer registry and verified through hospitals treating childhood cancers.SettingFinland, one of the countries most heavily contaminated by the Chernobyl accident; the population was divided into fifths by exposure.SubjectsChildren aged 0-14 years in 1976-92.Main Outcome MeasuresStandardised incidence ratio of childhood leukaemia and relative excess risk of childhood leukaemia per mSv. From incidence data of Finnish cancer registry for 1976-85, expected numbers specific to sex and age group (0-4, 5-9, and 10-14 years) were calculated for each municipality for three periods (1976-85, 1986-8, and 1989-92) and pooled as exposure fifths. Dose response was estimated as regression slope of standardised incidence ratios on mean doses for fifths for each period.ResultsPopulation weighted mean effective doses for first two years after the accident were 410 microSv for the whole country and 970 microSv for the population fifth with the highest dose. In all Finland the incidence of childhood leukaemia did not increase 1976-92. The relative excess risk 1989-92 was not significantly different from zero (7% per mSv; 95% confidence interval -27% to 41%).ConclusionsAn important increase in childhood leukaemia can be excluded. Any effect is smaller than eight extra cases per million children per year in Finland. The results are consistent with the magnitude of effect expected.

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