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Mayo Clinic proceedings · Apr 2020
ReviewUpdate on Treatment of Clostridioides difficile Infection.
- Janice M Cho, Darrell S Pardi, and Sahil Khanna.
- Department of Internal Medicine, Mayo Clinic, Rochester, MN.
- Mayo Clin. Proc. 2020 Apr 1; 95 (4): 758-769.
AbstractClostridioides difficile infection (CDI) is the leading cause of health care-associated infections in the United States. The increasing incidence and recurrence rates of CDI together with its associated morbidity and mortality are great concerns. Newer treatment methods, such as narrow-spectrum antibiotics, monoclonal antibodies, and microbial replacement therapies, are being developed and implemented. We searched PubMed to identify published literature from 2010 to 2018 using the following keywords: Clostridium difficile, treatment, and therapy. Cited references were also used to identify relevant literature. This review focuses on the current standard of therapy and emerging therapies for CDI and summarizes the updated guidelines on treatment of CDI.Copyright © 2019 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
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