• Kefu Liu, Yuanying Zeng, Ping Xie, Xun Ye, Guidong Xu, Jian Liu, Hao Wang, and Jinxian Qian.
• Department of Medical imaging.
• Medicine (Baltimore). 2020 May 1; 99 (18): e20175.

RationaleThe cystic features of the novel coronavirus disease 2019 (COVID-19) found on computed tomography (CT) have not yet been reported in the published literature. We report the cystic chest CT findings of 2 patients confirmed to have COVID-19-related pneumonia.Patient ConcernsA 38-year-old man and a 35-year-old man diagnosed with severe COVID-19 pneumonia were admitted to the intensive care unit.DiagnosesChest CT findings showed multiple cysts in ground-glass opacities (bilaterally) with/without pneumothorax. The cysts had a smooth inner wall.InterventionsThe patients continued to be given oxygen by mask and received antitussive, phlegm-dispelling treatment.OutcomesAt follow up, there was a reduction in the number of multiple cystic lesions on CT. To date, 1 patient was discharged from hospital, while the other had been transferred to the rehabilitation department.LessonsCOVID-19 may independently result in pulmonary cyst formation and pneumothorax; the application of a ventilator may be another causative factor.

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