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- Ru Chen, Ke-Xin Wang, Xue Meng, and Wen Zhou.
- Department of Respiratory Medicine.
- Medicine (Baltimore). 2020 May 1; 99 (20): e20241.
BackgroundThis study aims to investigate the efficacy and safety of benralizumab for the treatment of patients with chronic obstructive pulmonary disease (COPD).MethodsThis study will systematically and comprehensively search relevant literatures in electronic databases (MEDLINE, EMBASE, Cochrane Library, Global health, PsycINFO, Scopus, WANGFANG, and CNKI) from inception to the present without language and publication time restrictions. Two reviewers will independently carry out literature identification, data collection, and study quality assessment. Any disagreement will be settled down by a third reviewer through discussion and a consensus will be reached. RevMan 5.3 software will be used for statistical analysis performance.ResultsThis study will summarize up-to-date evidence to assess the efficacy and safety of benralizumab for the treatment of COPD.ConclusionThe findings of this study will provide helpful evidence to determine whether benralizumab is effective or not for the treatment of COPD.Systematic Review RegistrationINPLASY202040039.
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