• Medicine · May 2020

    Case Reports

    Refractory adult Coats disease treated with dexamethasone intravitreal implant: A case report.

    • Yu-Hua Ding, Bang-Tao Yao, Xiao-Gui Zhao, Hao Yu, Gang Liu, and Xiu-Ying Wang.
    • Department of Ophthalmology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University.
    • Medicine (Baltimore). 2020 May 1; 99 (20): e20249.

    IntroductionCoats disease is a sporadic, retinal vascular abnormality, causing blindness. Several interventional methods, including laser photocoagulation, have been proposed; however, the use of intravitreal dexamethasone in refractory Coats disease is not well described.Patient ConcernsA 38-year-old man presented with a painless reduction in visual acuity in his right eye, commencing 15 days prior to initial assessment.DiagnosisClinical manifestations and multimodal imaging indicated Coats disease.InterventionsRetinal laser photocoagulation was performed in the nonperfused areas, 15 months later, the exudative retinal detachment, and macular edema remained, the patient was then treated with an intravitreal slow-release dexamethasone implant.OutcomesThe exudative retinal detachment and macular edema had resolved, and the BCVA had also improved.ConclusionDexamethasone intravitreal implantation was effective in treating refractory Coats disease.

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