• Quan Wang, Yijun Zhang, Jingyu Du, and Xiangjin Lin.
• Department of Orthopedics, The First Affiliated Hospital of Zhejiang University, Hangzhou City, China.
• Medicine (Baltimore). 2020 May 29; 99 (22): e19995e19995.

BackgroundCurrently, there remains a paucity of literature about the efficiency of proximal adductor canal block (PACB) versus distal adductor canal block (DACB) for pain management after total knee arthroplasty (TKA). The purpose of this study is to perform a randomized controlled trial to compare the efficiency of PACB versus DACB for early postoperative pain treatment after TKA.MethodsThis study is a 2-arm, parallel-group, randomized controlled trial that is conducted at a single university hospital in China. Subjects presenting for unilateral TKA are randomized in a 1:1 ratio to either a PACB or DACB group. The primary outcome of this noninferiority study is opioid consumption within the first 24 hours following surgery. Secondary outcomes include quadriceps strength, pain scores, distance ambulated, and patient satisfaction. Continuous variables are compared using Student t test.ResultsThis clinical trial is expected to provide evidence of whether the PACB and DACB provide similar analgesia after TKA.Trial RegistrationThis study protocol was registered in Research Registry (researchregistry5440).

9 keywords...

hide…