• Francesco Corallo, Simona De Salvo, Cecilia Cannistraci, Viviana Lo Buono, Marcella Di Cara, Daniela Floridia, Francesco Cerra, Laura Romeo, Deborah Pria, Placido Bramanti, Silvia Marino, and Lilla Bonanno.
• IRCCS Centro Neurolesi "Bonino Pulejo," S.S. 113 C.da Casazza, Messina, Italy.
• Medicine (Baltimore). 2020 May 29; 99 (22): e20490.

AbstractChronic pain can have a devastating impact and lead to patient isolation. Many people with chronic pain are predisposed to anxiety-depressant symptoms, due to a lower quality life. The aim of the study is to demonstrate how neuromodulation methods, can encourage the reduction of chronic pain and an improvement in the quality of life, therefore advancing the restoration of psychological well-being.We involved 50 patients with a diagnosis of pain that not respond to traditional pharmacological therapies. Interventions: All subject had depression and anxiety symptoms and a low-quality life. We used the spinal cord stimulation treatment and a psychological evaluation for assessment of depression-anxiety symptomatology and the level of quality life.We observed a significant difference in physical functioning, role limitations due to physical health, general health perceptions, vitality, social functioning, role limitations due to emotional problems and mental health.Our study affirms that the perception of chronic pain has a great impact on the perception of psychological well-being, quality of life, and the performance of normal daily social and professional activities.

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