• Cleve Clin J Med · Dec 2019

    Review

    Functional heartburn: An underrecognized cause of PPI-refractory symptoms.

    • Scott Gabbard and Sonya Vijayvargiya.
    • Department of Gastroenterology, Hepatology & Nutrition, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH gabbars@ccf.org.
    • Cleve Clin J Med. 2019 Dec 1; 86 (12): 799-806.

    AbstractFunctional heartburn--persistent symptoms of esophageal reflux with no objective evidence of gastroesophageal reflux disease (GERD)--is the most common cause of failure of proton pump inhibitor (PPI) therapy, but it is often overlooked by internists and gastroenterologists.Copyright © 2019 Cleveland Clinic.

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