• Cleve Clin J Med · Dec 2019

    Review

    Gabapentin for alcohol use disorder: A good option, or cause for concern?

    • Vania Modesto-Lowe, Gregory C Barron, Benjamin Aronow, and Margaret Chaplin.
    • University of Connecticut School of Medicine, Farmington, CT.
    • Cleve Clin J Med. 2019 Dec 1; 86 (12): 815-823.

    AbstractThe anticonvulsant drug gabapentin is used off-label to treat alcohol-related withdrawal, cravings, anxiety, and insomnia. Although it is well tolerated and has demonstrated efficacy for mild alcohol withdrawal and early abstinence, there is concern about its potential for abuse. Gabapentin should be prescribed only as a second-line alternative to standard therapies, and only after screening for opioid or other prescription drug abuse to determine if heightened monitoring is warranted. Clinicians should be aware of gabapentin's limitations for treating alcohol use disorder and be attentive to emerging data on risks and benefits.Copyright © 2019 Cleveland Clinic.

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