• Cleve Clin J Med · Apr 2020

    CGRP antagonists for decreasing migraine frequency: New options, long overdue.

    • Julia Bucklan and Zubair Ahmed.
    • Center for General Neurology, Department of Neurology, Cleveland Clinic bucklaj@ccf.org.
    • Cleve Clin J Med. 2020 Apr 1; 87 (4): 211-218.

    AbstractThe cornerstone of preventive migraine treatment has long been drugs developed for other diseases such as epilepsy, depression, and hypertension. But a new set of drugs is available for preventing migraine attacks: erenumab, galcanezumab, fremanezumab, and eptinezumab. These monoclonal antibodies target calcitonin gene-related peptide (CGRP) or its receptors, each a key molecule in the pathophysiology of migraine.Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.

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