• Cleve Clin J Med · Sep 2020

    Hydroxychloroquine use in the COVID-19 patient.

    • Emily Littlejohn.
    • Department of Rheumatologic and Immunologic Disease, Orthopaedic & Rheumatologic Institute, Cleveland Clinic LITTLEE3@ccf.org.
    • Cleve Clin J Med. 2020 Sep 2.

    AbstractHydroxychloroquine (HCQ) has multiple potential antiviral mechanisms of action that differ according to the pathogen studied (eg, Chikungunya, Dengue virus, human immunodeficiency virus, poliovirus, Zika virus). Data on HCQ for treatment of COVID-19 are rapidly evolving. To date, there is no evidence from randomized controlled trials that HCQ, or any single therapy, improves outcomes in patients infected with COVID-19. There are also no clinical trial data supporting prophylactic HCQ therapy in COVID-19. Use of HCQ in patients with COVID-19 is being investigated for prophylaxis, postexposure prophylaxis, and treatment.Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.

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