• Cleve Clin J Med · Oct 2020

    Practical aspects of targeting IL-6 in COVID-19 disease.

    • Cassandra Calabrese, Prabalini Rajendram, Gretchen L Sacha, and Leonard Calabrese.
    • Cleveland Clinic CALABRC@ccf.org.
    • Cleve Clin J Med. 2020 Oct 7.

    AbstractInterleukin 6 (IL-6) took center stage as a therapeutic target, given its role in the cytokine storm phase of COVID-19. While IL-6 inhibitors have been widely used to treat a variety of immune-mediated disease states, they have not been used often in the intensive care setting, and new data question their efficacy. This brief review provides practical information on their administration and safety.Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.

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