• Donna R Shelley, Thomas Gepts, Nina Siman, Ann M Nguyen, Charles Cleland, Allison M Cuthel, Erin S Rogers, Olugbenga Ogedegbe, Hang Pham-Singer, Winfred Wu, and Carolyn A Berry.
• Department of Policy and Public Health Management, College of Global Public Health, New York University, New York, New York. Electronic address: donna.shelley@nyu.edu.
• Am J Prev Med. 2020 May 1; 58 (5): 683-690.

IntroductionPractice facilitation is a promising practice transformation strategy, but further examination of its effectiveness in improving adoption of guidelines for multiple cardiovascular disease risk factors is needed. The objective of the study is to determine whether practice facilitation is effective in increasing the proportion of patients meeting the Million Hearts ABCS outcomes: (A) aspirin when indicated, (B) blood pressure control, (C) cholesterol management, and (S) smoking screening and cessation intervention.Study DesignThe study used a stepped-wedge cluster RCT design with 4 intervention waves. Data were extracted for 13 quarters between January 1, 2015 and March 31, 2018, which encompassed the control, intervention, and follow-up periods for all waves, and analyzed in 2019.Setting/ParticipantsA total of 257 small independent primary care practices in New York City were randomized into 1 of 4 waves.InterventionThe intervention consisted of practice facilitators conducting at least 13 practice visits over 1 year, focused on capacity building and implementing system and workflow changes to meet cardiovascular disease care guidelines.Main Outcome MeasuresThe main outcomes were the Million Hearts' ABCS measures. Two additional measures were created: (1) proportion of tobacco users who received a cessation intervention (smokers counseled) and (2) a composite measure that assessed the proportion of patients meeting treatment targets for A, B, and C (ABC composite).ResultsThe S measure improved when comparing follow-up with the control period (incidence rate ratio=1.152, 95% CI=1.072, 1.238, p<0.001) and when comparing follow-up with intervention (incidence rate ratio=1.060, 95% CI=1.013, 1.109, p=0.007). Smokers counseled improved when comparing the intervention period with control (incidence rate ratio=1.121, 95% CI=1.037, 1.211, p=0.002).ConclusionsIncreasing the impact of practice facilitation programs that target multiple risk factors may require a longer, more intense intervention and greater attention to external policy and practice context.Trial RegistrationThis study is registered at www.clinicaltrials.gov NCT02646488.Copyright © 2020 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

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