• Roman Pavić, Robert Blažeković, Dalibor Divković, Ksenija Marjanović, and Mirna Sipl.
• 1Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 2Department of Traumatology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 3Department of Surgery, Dubrava University Hospital, Zagreb, Croatia; 4Department of Pediatric Surgery, Osijek University Hospital Centre, Osijek, Croatia; 5Department of Pathology and Forensic Medicine, Osijek University Hospital Centre, Osijek, Croatia; 6Department of Pediatrics, Osijek University Hospital Centre, Osijek, Croatia.
• Acta Clin Croat. 2019 Sep 1; 58 (3): 535-539.

AbstractTakayasu's arteritis (TA) affects the aorta and its branches. Immunosuppressants are the usual course of therapy, while surgery has been used in acute cases. There is only scant information on TA in infancy, and the nonspecific symptoms in the initial stage of the disease make the diagnosis difficult and delayed, thus increasing the mortality rate. We describe a case of aggressive progression of TA in an infant. This child was the youngest to be affected with the disease as reported in the literature. A 3.5-month-old boy presented with cyanosis of both legs, tachycardia and antithrombin III deficiency. Computed tomography angiography (CTA) revealed thrombosis of distal aorta and both iliac arteries. Thrombectomy was performed at the level of both common femoral arteries. In addition, thigh amputation of the left leg had to be performed. TA was diagnosed postmortem with thrombosis of the distal aorta, its branches and upper mesenteric artery which was not occluded on previous CTA, glomerulonephritis and pulmonary parenchymal granulomatous infiltrations.

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