• Acta clinica Croatica · Sep 2019

    Case Reports

    Nocardial brain abscess mimicking lung cancer metastasis in immunocompetent patient with pulmonary nocardiasis: a case report.

    • Mladen Karan, Nada Vučković, Petar Vuleković, Ante Rotim, Nebojša Lasica, and Lukas Rasulić.
    • 1Department of Surgery, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; 2Department of Pathology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; 3Department of Neurosurgery, Clinical Centre of Vojvodina, Novi Sad, Serbia; 4Pathology and Histology Center, Clinical Centre of Vojvodina, Novi Sad, Serbia; 5Department of Neurosurgery, Dubrava University Hospital, Zagreb, Croatia; 6Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 7Department of Neurosurgery, Clinical Centre of Serbia, Belgrade, Serbia.
    • Acta Clin Croat. 2019 Sep 1; 58 (3): 540-545.

    AbstractNocardia is a ubiquitous microorganism which can be the cause of local and disseminated infection in humans. Immunocompetent and immunocompromised patients both can be affected and Nocardia cyriacigeorgica was reported as a pathogen isolated in patients worldwide. In most cases, nocardiosis is present as pulmonary infection because inhalation is the primary way of bacterial exposure. Nocardial brain abscess occurs usually secondary to a septic focus elsewhere in the body. Considering the facts that the elderly population is growing, such as the number of immunocompromised patients together with high mortality rate in patients with nocardial infection of the central nervous system, we have to raise awareness of the possibility for this rare but potentially fatal condition. We present a case where nocardial abscesses of lung and brain were initially suspected as lung cancer with brain metastases. The patient was treated with a combination of surgical resection and antimicrobial therapy with good outcome.

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