African health sciences
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African health sciences · Jun 2007
Functional adrenal insufficiency among critically ill patients with human immunodeficiency virus in a resource-limited setting.
Functional adrenal insufficiency (FAI) is associated with increased mortality and is defined as subnormal cortisol production during acute severe illness. ⋯ The diagnosis of FAI should be considered in severely ill patients with stage IV HIV disease using rifampicin or those found to have unexplained eosinophilia. Further studies to determine benefits of corticosteroids in critically ill HIV patients are needed in this setting.
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African health sciences · Jun 2007
Effect of HIV-1 infection on malaria treatment outcome in Ugandan patients.
Malaria and HIV-1 infection cause significant morbidity and mortality in sub-Saharan Africa. HIV-1 increases risk for malaria with the risk increasing as immunity declines. The effect of HIV-1 infection on antimalarial treatment outcome is still inconclusive. ⋯ Adherence to cotrimoxazole prophylaxis should be reinforced in HIV positive patients and it should be reassessed if these patients present with acute episodes of malaria.
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African health sciences · Jun 2007
Epidemiological factors that promote the development of severe malaria anaemia in children in Ibadan.
Effective control and management of severe malaria cases depends on a clear understanding of the local epidemiological factors and specific clinical manifestations of the disease in the different endemic regions. ⋯ The study underscores the need for community involved partnership for malaria control especially through health education for the home management of malaria, especially among those experiencing some form of inequity in access to healthcare.