African health sciences
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African health sciences · Dec 2011
The efficacy of the crude root bark extracts of Erythrina abyssinica on rifampicin resistant Mycobacterium tuberculosis.
Tuberculosis (TB) is one of the leading causes of morbidity and mortality with a global mortality rate at two million deaths per year while one third of the world's population is infected with the TB bacillus. ⋯ The conclusion from the study was that Erythrina abbyssinica has antimycobacterial activity and reasonable safety that merits further research.
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African health sciences · Dec 2011
Case ReportsPhenotype-genotype analysis of dystrophinopathy caused by duplication mutation in Dystrophin gene in an African patient.
The dystrophinopathies, duchenne muscular dystrophy (DMD) and Becker muscular dystrophy are common X-linked genetic myopathies resulting from mutations in the dystrophin gene. Duplication is an uncommon mechanism of mutation occurring in about 5% of DMD cases. The global prevalence of DMD is reported as 1/18,000 males. There is little clinical or epidemiological data on African patients. ⋯ This case extends the world wide epidemiology of this disease to include the African/Ghanaian population and confirms the vulnerability of the dystrophin gene to recurrent spontaneous mutations at the exon 8 and 9 site.
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African health sciences · Dec 2011
The pattern, clinical characteristics and outcome of ESRD in Ile-Ife, Nigeria: is there a change in trend?
The prevalence of chronic renal failure and End Stage Renal Disease (ESRD) has remained high worldwide and the epidemiology has changed significantly in the last decade in industrialised countries. While there have been significant improvements in these patient's outcomes in developed countries, their state and survival is still appalling in developing countries. ⋯ End stage renal disease is still prevalent with chronic glomerulonephritis and hypertension being the common causes. Prognosis is still grave hence subsidized renal replacement therapy and preventive nephrology should be targeted in such underserved populations.
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Caesarean section birth is a frequent mode of delivery worldwide. Several social factors have been demonstrated to be strong predictors of caesarean births. ⋯ Rate of caesarean delivery in Italy is rather high. Age and residence are the sole social predictors evidenced from the ISTAT 2005 survey data.