African health sciences
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African health sciences · Jun 2014
Is consanguinity prevalence decreasing in Saudis?: A study in two generations.
Saudi population is unique in that there is a strong preference for cousin marriages in the general population. We studied the prevalence of consanguinity in educated Saudi females and compared the results with the results obtained in their parents, to access if a generation difference in which extensive educational activities have prevailed to inform the people of the influence of cousin marriages on health, has made any difference in prevalence of consanguineous marriages. ⋯ The results did not reveal any decrease in the prevalence of consanguinity over a generation. This shows that the tradition of marrying within the family is a preferred practice, despite the awareness that certain genetic disorders occur at a higher frequency in cousin marriages. There is a need at the primary health care level to inform the public of the consequences of this common practice.
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African health sciences · Jun 2014
Decreased levels of circulating sex hormones as a biomarker of lung cancer in male patients with solitary pulmonary nodules.
An early differentiation of malignant from benign solitary pulmonary nodules (SPNs) is essential for management and prognosis of lung cancer. ⋯ The reduced sex hormones levels seemed to be uniquely associated with lung cancer. Therefore, measurement of sex hormones may have clinical potential in the diagnosis of malignancy in patients with SPNs.
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African health sciences · Jun 2014
ReviewDental approach to erosive tooth wear in gastroesophageal reflux disease.
The duration of gastro-esophageal reflux disease (GERD), the frequency of reflux, the pH and type of acid, and the quality and quantity of saliva affect the severity of dental erosion due to GERD. ⋯ Diagnosing the cause of erosive tooth wear can help prevent further damage. Patients must be informed about how to prevent GERD.
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African health sciences · Jun 2014
Case ReportsNovel nonsense mutation of BRCA2 gene in a Moroccan man with familial breast cancer.
Breast cancer is the most common cancer in women worldwide. About 5 to 10% of cases are due to an inherited predisposition in two major genes, BRCA1 and BRCA2, transmitted as an autosomal dominant form. Male breast cancer is rare and is mainly due to BRCA2 than BRCA1 germline mutations. ⋯ Identification of novel heterozygous germline mutation c.6428C>A ; p.Ser2143Stop of BRCA2 gene.
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African health sciences · Jun 2014
Comparative StudyLiver enzymes and psychological well-being response to aerobic exercise training in patients with chronic hepatitis C.
Chronic hepatitis C (CHC) is a medical condition that has broad implications for a person's physical and psychological health. ⋯ Aerobic exercise training improves hepatic enzymes and psychological well-being in patients with chronic hepatitis C.