African health sciences
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African health sciences · Dec 2017
The market dynamics of selective serotonin re-uptake inhibitors: a private sector study in South Africa.
The objective of this study was to analyse the market share of generic vs originator selective serotonin re-uptake inhibitors (SSRIs), and also compare market share of different SSRIs in the private health care sector in South Africa, over a period of 4 years. ⋯ In line with policies, generic SSRIs hold a larger volume of the market in the private sector in South Africa.
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African health sciences · Dec 2017
Long term effect of a school based intervention to prevent chronic diseases in Tunisia, 2009-2015.
We aimed to evaluate the long term effect of school based intervention to prevent non- communicable disease risk factors. ⋯ The present work showed that interventions promoting healthy lifestyles should be maintained. Developing countries should be encouraged and supported to design, conduct, and evaluate robust preventive interventions.
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African health sciences · Dec 2017
Role of offending out-door aero-allergen and CD14 C(-159)T polymorphism in development and severity of asthma in a Kolkata patient population.
Present study involved identification of offending out-door aero-allergens and associated genetic pathway in nasso-bronchial asthma among Kolkata population. ⋯ In Kolkata, pollen is a common out-door aero-allergen and Cocos nucifera is predominant among pollens. Childhood-onset and adult-onset of asthma showed significant difference in allergen sensitivity as well as genetic background with respect to CD14 polymorphism.
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Breast cancers metastasizing to thyroid gland are relatively uncommon in clinical practice. ⋯ US was useful in screening TM in breast cancer patients. Both partial and total thyroidectomy was effective in disease free survival of isolated TM cases, with controlled primary condition. TM responded well to chemotherapy in most of the recurrent breast cancer cases with or without distant metastasis.
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African health sciences · Dec 2017
The effect of interrupted anti-retroviral treatment on the reconstitution of memory and naive T cells during tuberculosis treatment in HIV patients with active pulmonary tuberculosis.
The reconstitution of cellular immune components contributes to clinical outcome of HIV and Mycobacterium tuberculosis (MTB) infection. Interruption of anti-retroviral therapy (ART) could lead to perturbations in reconstitution of T cells in HIV/ tuberculosis (TB) patients. ⋯ Interrupting ART alters CD8+ but not CD4+ sub-sets in patients with less advanced HIV infection and TB.