African health sciences
-
African health sciences · Mar 2017
Observational StudyDistribution of symptoms of post-stroke depression in relation to some characteristics of the vulnerable patients in socio-cultural context.
To determine the distribution of symptoms of post-stroke depression (PSD) in relation to some predisposing factors in an African population. ⋯ Age could be a risk factor for PSD, which was more prevalent in the elderly than young/middle-age adults, female gender, left cerebral lesion, complications, cold case; those living with a spouse, self-employed and unemployed.
-
African health sciences · Mar 2017
Comparative StudyHow weight during pregnancy influences the association between pre-pregnancy body mass index and types of delivery and birth: a comparison of urban and rural areas.
Women in study areas suffered from the problems of caesarean delivery (CD), low birth weight (LBW), and macrosomia. ⋯ These findings strongly support the need to reform adequate pre-pregnancy weight and GWG against the risks of CD and macrosomia among overweight and obese women, and against the risk of LBW among lean women in both areas.
-
African health sciences · Mar 2017
Renal histoarchitectural changes in nevirapine therapy: possible role of kolaviron and vitamin C in an experimental animal model.
There is paucity of literature regarding the nephrotoxicity of antiretroviral drugs and its interaction with plant-based adjuvants. This study investigates the attenuating effect of kolaviron in nevirapine-therapy on the histological structure of the kidneys of adult male Sprague-Dawley rats. ⋯ Adjuvant treatment with kolaviron (an anti-oxidant) for 56 days appears to attenuate the nephrotoxicity of nevirapine in this model.
-
African health sciences · Mar 2017
Randomized Controlled TrialA randomized controlled trial to assess the effect of a ketamine infusion on tourniquet hypertension during general anaesthesia in patients undergoing upper and lower limb surgery.
Tourniquet hypertension arising from tourniquet inflation remains a primary concern to the anaesthetist. One drug commonly used to manage tourniquet hypertension is ketamine. No studies have examined the effect of ketamine on tourniquet hypertension for a period of more than one hour or an infusion of the same. ⋯ Based on the results of this study, there was a difference in the proportion of tourniquet hypertension between the ketamine and saline groups for patients undergoing upper and lower limb orthopaedic surgery under general anaesthesia.
-
African health sciences · Mar 2017
Meta AnalysisAssociation between ALDH2 Glu504Lys polymorphism and colorectal cancer risk: a meta-analysis.
The findings from studies on the relationship between aldehyde dehydrogenases(ALDH) gene Glu504Lys polymorphism and colorectal cancer(CRC) were inconsistent. ⋯ This meta-analysis suggests that the ALDH2 Glu504Lys polymorphism may be associated with susceptibility to CRC. Furthermore, large and well-designed studies are needed to confirm these conclusions.