African health sciences
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African health sciences · Mar 2021
Meta AnalysisThe efficacy of dapagliflozin for type 1 diabetes: a meta-analysis of randomized controlled studies.
The efficacy of dapagliflozin for type 1 diabetes remains controversial. We conduct a systematic review and meta-analysis to explore the treatment efficacy of dapagliflozin versus placebo in patients with type 1 diabetes. ⋯ Dapagliflozin treatment benefits to reduce HbA1c and FPG for type 1 diabetes.
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African health sciences · Mar 2021
Multicenter StudyCharacteristics and outcomes of patients with multiple myeloma at the Uganda Cancer Institute.
Data on multiple myeloma (MM) in sub-Sahara Africa is scarce. In Uganda, there is a progressively increasing incidence of MM over the years. ⋯ Most patients with multiple myeloma at the UCI were diagnosed at a relatively young age, presented with late stage disease and bone pain, and had a shorter survival time. Factors associated with worse survival were Durie-Salmon stage III and LDH >225 U/L.
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African health sciences · Mar 2021
Meta AnalysisIndian scenario of IgA nephropathy: a systematic review and meta-analysis.
IgA nephropathy (IgAN) is most common primary glomerulopathy. There are variations in prevalence of IgAN and its clinical features in different studies from India. ⋯ The overall prevalence of primary IgAN in India was 16.5%. The subnephrotic proteinuria and microscopic hematuria were common clinical features.
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African health sciences · Mar 2021
Distribution of phthisis bulbi and status of fellow eyes at a tertiary eye-care centre in Nigeria: a ten-year review.
Phthisis bulbi is an irreversible cause of visual loss with insufficient evidence about its aetiology and status of patients' fellow eyes. ⋯ The commonest cause of phthisis bulbi was trauma. Approximately nine out of ten patients had ocular morbidities in their fellow eye. A thorough follow-up of patients with phthisis bulbi is recommended.