African health sciences
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African health sciences · Mar 2021
Anti-inflammatory potential of dichloromethane leaf extracts of Eucalyptus globulus (Labill) and Senna didymobotrya (Fresenius) in mice.
Inflammation is an immune response characterized by swelling, redness, pain and heat. Inflammation is mainly managed using conventional medicines that are associated with many side effects. Plant-based remedies are considerably better alternative therapies for they have fewer side effects. ⋯ E. globulus and S. didymobotrya have potent anti-inflammatory activities, attributed to their constituent phytochemicals. This study confirms the traditional use of these plants in treating inflammation.
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African health sciences · Mar 2021
Meta AnalysisThe efficacy of dapagliflozin for type 1 diabetes: a meta-analysis of randomized controlled studies.
The efficacy of dapagliflozin for type 1 diabetes remains controversial. We conduct a systematic review and meta-analysis to explore the treatment efficacy of dapagliflozin versus placebo in patients with type 1 diabetes. ⋯ Dapagliflozin treatment benefits to reduce HbA1c and FPG for type 1 diabetes.
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African health sciences · Mar 2021
Meta AnalysisIndian scenario of IgA nephropathy: a systematic review and meta-analysis.
IgA nephropathy (IgAN) is most common primary glomerulopathy. There are variations in prevalence of IgAN and its clinical features in different studies from India. ⋯ The overall prevalence of primary IgAN in India was 16.5%. The subnephrotic proteinuria and microscopic hematuria were common clinical features.
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African health sciences · Mar 2021
Risk factors of multidrug-resistant bacteria in community-acquired urinary tract infections.
Urinary tract infections (UTIs) are one of the most seen infection among community. ⋯ Doctors should consider prescribing broad-spectrum antibiotics in patients with severe UTIs with a history of UTI, advanced age, male gender, and multiple antibiotic usage, even if they have a CA-UTI.
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African health sciences · Mar 2021
Review Case ReportsIsolated acute pseudobulbar palsy with infarction of artery of percheron: case report and literature review.
Pseudobulbar palsy (PBP) is characterized by supranuclear lesions in the corticobulbar pathway. Neoplasia, inflammatory, demyelinating, and stroke are possible etiologies of this disorder. ⋯ To the authors' knowledge, there are two cases of individuals with artery of Percheron infarction who developed PBP associated with other clinical syndromes. Still, isolated PBP following infarction of Percheron's artery was not reported. We hypothesized that the PBP may have occurred because of the existence of vascular territory variations in the perforating arteries that arise from the AOP.