African health sciences
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African health sciences · Mar 2021
The impact of selenium administration on severe sepsis or septic shock: a meta-analysis of randomized controlled trials.
The efficacy of selenium administration to treat severe sepsis or septic shock remains controversial. We conduct a systematic review and meta-analysis to explore the impact of selenium administration on severe sepsis or septic shock. ⋯ Selenium administration results in notable decrease in all-cause mortality and length of hospital stay, but shows no substantial influence on the 28-day mortality, length of ICU stay, duration of vasopressor therapy, the incidence of acute renal failure, adverse events, and serious adverse events for septic patients.
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African health sciences · Mar 2021
Multicenter StudyCharacteristics and outcomes of patients with multiple myeloma at the Uganda Cancer Institute.
Data on multiple myeloma (MM) in sub-Sahara Africa is scarce. In Uganda, there is a progressively increasing incidence of MM over the years. ⋯ Most patients with multiple myeloma at the UCI were diagnosed at a relatively young age, presented with late stage disease and bone pain, and had a shorter survival time. Factors associated with worse survival were Durie-Salmon stage III and LDH >225 U/L.
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African health sciences · Mar 2021
What differs former, light and heavy smokers? Evidence from a post-conflict setting.
Evidence suggests that people who live in regions affected by the armed conflict are more likely to smoke. ⋯ Smoking prevention and cessation programs should include the entire community, because exposure to environmental second hand smoke may facilitate initiation and more intense smoking. Screening of student smokers for depression should be prioritized in the process of rebuilding the framework for primary and secondary prevention in the post-conflict period.
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African health sciences · Mar 2021
Relationship of oxidative stress and antioxidant response with vaso-occlusive crisis in sickle cell anaemia.
Though sickle cell anaemia (SCA) is known to promote oxidative stress, there is paucity of information on the relationship between oxidative stress and vaso-occlusive crisis (VOC). ⋯ Sickle cell anaemia exhibited oxidative stress and alteration in the levels of antioxidant indices which was possibly associated with vaso-occlusive crisis.
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African health sciences · Mar 2021
Risk factors for hazardous drinking in university students from South Africa and Belgium: a cross-cultural comparison study.
Previous studies have associated certain risk factors with hazardous drinking in students. However, big cultural and geographical differences exist regarding alcohol use. ⋯ This study found a significant difference in hazardous drinking between Belgian and South African university students.