African health sciences
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African health sciences · Dec 2022
Investigation of the effects of mir-219-1 gene variants on the development of disease in non-small cell lung cancer patients.
Various variants of the miR-219-1 gene are one of the first genes associated with NSCLC prognosis in the literature. ⋯ miRNA single nucleotide polymorphisms can be used as genetic biomarkers to predict cancer susceptibility, early diagnosis, and prognosis. Our study has shown that two variants of miR-219-1 were not related to NSCLC in the Turkish population. The reason for this can be differences in ethnicity, regions, and background of population and these differences could lead to various outcomes.
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African health sciences · Dec 2022
Discontinuation of contraceptives among adolescent girls aged 15-19 years in Nigeria: a descriptive analysis.
Adolescent girls are the mostly affected with maternal and child complications. Contraceptive use is an important tool in curbing sexual and reproductive health challenges especially among adolescent girls in the developing countries. Despite, the low use of contraceptives among adolescents in Nigeria, the possibility of discontinuation of use after initiation is strong. ⋯ One in five of unmarried adolescents who ever use a method, discontinue use because of sexual frequency and type of method used.
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African health sciences · Dec 2022
Traditional medicine trade and uses in the surveyed medicine markets of Western Kenya.
There exist vast traditional medicine and herbal remedies prescribed for diseases and socio-cultural ills that are sold in local medicine markets. ⋯ Traditional medicine traded in the local medicine markets continue to play a significant role in the treatment of common diseases. Frequently traded medicinal plant species should be prioritized for conservation.
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African health sciences · Dec 2022
Meta AnalysisA meta-analysis and experimental data for multidrug resistance genes in breast cancer.
Increasing trend of breast cancer incidence worldwide is a known fact. This curable disease may become fatal if drug resistance is developed leading to metastatic cancerous tissue. ⋯ These findings suggest that these genes are associated with breast cancer.